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Irene Muscarà was born in Messina, Sicily. She found her passion in acting at an early age, performing her first roles in the living room of her family house. In her teens, she participated in shows at the school theater and became interested in Stanislavki's system and Russian theater. Her interest was so strong that when she was 22, she moved to Moscow, Russia, to study cinema and theater acting at the Russian State Theater Academy. Her first outstanding role in theater was during her college years in Incredibly Loud And Extremely Close, a play inspired by J.S. Foer and directed by A. Shlyapin, which went on to tour in Los Angeles. Also there came out The Invention Of Love, a play by Tom Stoppard that was directed by A. Kuzmin-Tarasov, where Irene took the role of Professor Pattinson. When Tom Stoppard watched the play, he deeply appreciated the original interpretation of the character in the spirited performance of Irene. After graduating from the Academy in 2012, Irene inspired the production of Look At Me, a documentary by Anna Kolchina on the life of a young Italian actress in Moscow. It was awarded Best Film by the Documentary Film Festival in Saint Petersburg, after which the film traveled to NYC for the Russian Documentary Film Festival at the Tribeca Cinemas, winning the Special Jury prize. In 2013, Irene acted in the film The Calculator alongside Vinnie Jones. That year, she also played Producer Ornella, the villain in The Heritage, a period drama TV-series directed by A. Kasatkin. In 2015, Irene created a solo performance called Gate A 33, at the center of which stands the destiny of an old Russian woman waiting for her flight at an NYC airport. Irene won Best Actress for this work at the United Solo Festival in NYC. In 2018, Irene created a new one-woman show, Five Sisters, inspired by five female characters from A. P. Chekhov's plays. In 2019, she played the character of Prosperina in the HBO TV miniseries I Know This Much Is True, directed by Derek Cianfrance.
